You many be able to cobble something like you want with command pallette. Of course, every command would have to start with the key to show the command pallette , say f1, but then you could make custom action whose first letters of the name is the command sequence you want. For example, make a custom action named x23 and then in reaper hit f1 x23 <enter> and you will get that action. Clumsy and fragile but possible.